• 2000- present Head, Lab. of Pharmacology, Toxicology, & Material Biocompatibility, National Taiwan University Dental School • 2006.8-present Chair, Department of Endodontics, National Taiwan University Hospital • 2004.8-present Professor, National Taiwan University • 2006-present Adjunct Investigator, National Health Research Institute (NHRI), Taiwan

(1) Chemical carcinogenesis/Mutagenesis/transformation (2) Oral cancer: Biology and clinical research (3) Pharmacology & Toxicology and Pulp/periodontal Biology (4) Dental Materials (resin, sealers, glass ionomers, fluoride etc.) biocompatibility, growth factors (TGF-beta, thrombin etc.) and related mechanisms (5) Clinical endodontics (6) Angiogenesis, thrombosis & platelet function (7) Thrombin, fibrin, platelet-rich plasma, Integrin (8) Carcinogenesis & cell cycle control (9) Free Radical (reactive oxygen species) Biochemistry & Pathology (10) Oral cavity healthy & systemic diseases (11) Inflammatory Reaction, cytokines (IL-6 etc.) and prostanoids (PGE2, PGF2alpha etc.), receptor biology (12) Signal transduction (13) Animal studies (14) Atherosclerosis & vascular biology (15) Tumor cells-induced platelet activation