Dr. Jia obtained his Ph. D. in 2004 at School & Hospital of Stomatology, Wuhan University, China. After Ph. D. study, he went to HIV and AIDS malignancy Branch, Center for Cancer Research, National Cancer Institute, NIH, USA, as a visiting scientist from 2005 to 2010. He was Associated Professor from 2005 to 2012 and promoted to Full Professor in 2012 at Wuhan University. Dr. Jia’s research interests mainly focus on the development of effective anti-caries DNA vaccine and alternative splicing of pre-mRNA. Several methods have been developed to enhance the efficiency of anti-caries DNA vaccine, including a DNA vaccine targeting antigen-presenting cells by fusing CTLA-4 with antigens, co-immunization with chemokine CCL20 or CXCL13 expression plasmid, co-immunization with the shRNA expression plasmid against STAT3 to reduce the immunosuppression environment in mucosal immune system. He is also interested in the regulation of alternative splicing of pre-mRNA splicing, the role of alternative splicing in immune responses and immunosuppression, and the role of alternative splicing in tumorigenesis.

•Prevention of dental caries using vaccines •Anti-cancer DNA vaccine •RNA splicing and oral immune