Yue Zhang received his PhD degree from University of Fribourg, Switzerland in 2006; he and his colleague reported deficiency of TOR kinase doubles life span in C. elegans in Nature. He did his post-doc in University of Pittsburgh Medical Center and established DAF-12/Vitamin D receptor as development capacitor in C. elegans. Since 2008, first as research fellow, then promoted as instructor, he pursued cancer and Huntington's diseases research at Department of Radiation Oncology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston. In 2011, he started as senior scientist in Osteoarthritis (OA) Unit, University of Montreal Hospital Research Centre under directors professor Johanne Martel-Pelletier and professor Mohit Kapoor. His studies on the role of cartilage homeostasis mediator mTOR and autophagy pathway with patient specimens and model organisms led to novel strategy for OA prevention. There he worked as cartilage scientist in arthritis research center, Toronto Western Hospital, UHN. Now he works as full professor in The first Clinical college of Harbin Medical University, China.

Recent work includes the identification of OA biomarkers in cartilage and investigation of interrelationships among obesity, OA and autophagy. Current interests include studies on roles of Vitamin D receptor as health capacitor in autoimmune diseases such as rheumatic arthritis and associated cancers. Other interests include stem cell research and therapy, drug delivery and chemical modifications, policy of safety and security in healthcare facilities, and so on. As founding editor or executive editor of several journals,e.g. JNMRT, he also has some interests in publishing.