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Genital
condylomata are caused by infection with low-risk (non-oncogenic) types of
Human Papilloma Virus (HPV). Condylomata can be detected on the external
genitalia, vagina or cervix and are frequently multiple.
Condylomata
are mutiple, exophytic lesions, which are found in the vagina or on the vulva.
Depending on their size, they may be obvious to the naked eye. They present as
soft pink or white vascular growths with multiple, fine, finger-like
projections on the surface (Image 1).
Condylomata
have a typical appearance, with a vascular papilliferous or frond-like surface,
each element of which contains a central capillary (Image 2).
Often,
the surface of the lesion may be densely hyperplastic.
Occasionally,
the surface of a condyloma may have a whorled, heaped-up appearance with a
brain-like texture, known as an encephaloid pattern (Image 3).
These lesions
may be located inside the TZ but are more often found out-side the TZ (Image 4).
After the
application of acetic acid, there is blanching of the surface, with acetowhite
change persisting for some time (Image
5).
A
condyloma at the SCJ can sometimes be confused with a prominent area of
columnar epithelial villi. Both tend to be acetowhite, but a condyloma is
whiter.
Koilocytotic
cells exhibit vacuolization of the cytoplasm with condensation of the chromatin
and slight atypia of the nuclei (Image 6).
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