The gut mucosal immune system not only protects us from numerous pathogen invasion, but also maintains the homeostasis with commensal bacteria and innocuous food antigens. The failure of gut homeostasis not only increases the risk of gut infection, inflammatory bowel disease, but is also related to allergy, cancer,autoimmune, and metabolic diseases.Our lab’s goal is to combine molecular data with in vivo models to further the understanding of mechanisms underlying these homeostatic and pathological conditions and aid in the development of treatments for these gut related diseases.

Mucosal immunology, innate lymphoid cells, microbiota, gut related diseases