Editorial Board

Dr. M. Razzaghi-Abyaneh Ph.D

Dr. M. Razzaghi-Abyaneh Ph.D
Associate Professor & Head
Department of Mycology
Pasteur Institute of Iran
Iran

Biography :

Dr. Mehdi Razzaghi-Abyaneh was born in Tehran-Iran. He obtained his PhD degree in Mycology from Tarbiat Modares University (Iran, 2000). He pursued a training course on identification of antifungal compounds from bioactive plants at the Graduate School of Agriculture, Tokyo University, in the laboratory of Applied Biological Chemistry during 2006-2007. He is currently an associate professor and head of Mycology Department at the Pasteur Institute of Iran (Tehran, Iran), where he is working on mycotoxins and mycotoxigenic fungi for more than 10 years. His research interests encompass biologically active compounds of plant, fungal and bacterial origins with antifungal properties against a broad spectrum of fungal pathogens. He is also investigating ecology and genetic diversity of Aspergillus section Flavi especially aflatoxin-producing species from soil and other natural habitats. He has supervised a large number of PhD and MSc theses. He has published over fifty papers in international journals and a number of book chapters. He has demonstrated for the first time a phenylpropanoid compound named "Dillapiol" isolated from Anethum graveolens as the specific inhibitor of the biosynthesis of aflatoxin G group. He is working on the chemical basis of plant–fungal interactions and determining mode of action of antifungal compounds at cellular and molecular levels.

Research Interest :

Mycologist/Mycotoxicologist with experience in both teaching and research in Pasteur Institute of Iran and other resarch centers. The main area of my research interest is investigation on identification of natural inhibitors of fungal growth and secondary metabolite production from medicinal plants and bacteria. Involving also in the production of anti-aflatoxin monoclonal antibodies. Extensive experience in cell separation and fractionation, protein extraction and purification, enzyme manipulation, antibody production in experimantal animals (poly and monoclonal antibodies), chromatographic analyses of proteins and mycotoxins specially TLC and HPLC analysis of aflatoxins, identification and purification of effective inhibitors of aflatoxin biosynthesis from microorganisms and plants and electron microscopy of filamentous fungi. Demonstrated for the first time specific inhibitors of AFG series biosynthesis, Dillapiol and Apiol, from the essential oils of Anethum graveolens and Petroselinum crispum, respectively.