(1) A prospective study for assessment of role of Mesenchymal stem cell in knee joint pathology especially in osteoarthritis. (2) A prospective study for assessment of role of Cytokines and Growth Factors in knee joint pathology especially in osteoarthritis. (3) A prospective study for assessment of role of Cytokines and Growth Factors in meniscal ligament/tear and Cruciate ligament injury/tear. (4) A prospective study for assessment of role of Platelet Rich Plasma (PRP) in non-healing cutaneous ulcers patients. (5) A prospective study for assessment of role of growth factors in chronic musculoskletal injuries. (6) A prospective study for detection and identification of red cell alloantibodies in chronically transfused thalassemia Major patients.