Abstract
A Multidrug- Resistance Pattern of an Escherichia coli Strain Isolated from Diarrheal Stools at the China-Guinea Friendship Hospital of Kipe in Conakry
Abdoulaye Makanera*, Mariam Conde, Taliby Dos Camara, Mamadou Alpha Diallo, Mariama Conde, Daouda Camara, Alpha Oumar Barry, Tiguidanke Diakite and Oumar Souare
Corresponding Author: Abdoulaye Makanera, Biomedical Laboratory of the China-Guinea Friendship Hospital, Kipe, Cite des Médecins, Commune Ratoma 030 BP: 710 Conakry, Republic of Guinea.
Revised: November 28, 2023; Available Online: November 28, 2023
Citation: Makanera A, Conde M, Camara TD, Diallo MA, Conde M, et al. (2023) A Multidrug- Resistance Pattern of an Escherichia coli Strain Isolated from Diarrheal Stools at the China-Guinea Friendship Hospital of Kipe in Conakry. J Infect Dis Res, 6(S4): 01.
Copyrights: ©2023 Makanera A, Conde M, Camara TD, Diallo MA, Conde M, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Introduction: Diarrheal infections associated to multidrug resistant bacteria are a public health problem, particularly in the tropics.

Objective: The aim of this study was to describe a Multidrug resistant strain of Escherichia coli (E. coli) isolated from diarrheal stools.

Patients and Methods: A sample of diarrheal stools from a 30 years old housekeeper patient was analyzed at China Guinea Friendship Hospital of Kipé/Conakry. Parasitological examination by optical microscopy, followed by bacteriological analysis were done. Cultures were carried out on different agar media. Bacterial identification, antibiograms and minimum inhibitory concentrations (MIC) were performed using the Vitek 2 System.

Results: The isolated E. coli strain was sensitive only to 4 of 29 antibiotics tested including imipenem, ertapenem, amikacin and nitrofurantoin. Intermediate sensitivity was detected towards minocycline. In contrast, this strain was resistant to piperacillin, cefuroxime, cefuroxime axetil, cefixime, ceftriaxone, cefepime, aztreonam, meropenem, levofloxacin, ofloxacin, tetracycline, tigecycline, chloramphenicol, trimethoprim, ampicillin, amoxicillin/clavulanic acid, ticarcillin, piperacillin/tazobactam, cephalothin, cefotaxime, ceftazidime, gentamicin, tobramycin, nalidixic acid, ciprofloxacin, ofloxacin and trimethoprim/sulfamethoxazole with high MICs.

Conclusion: The treatment of this multidrug-resistant Escherichia coli diarrheal infection requires appropriate antibiotic therapy, based on the results of an accurate antibiogram to be performed with rapid means for better patient care.

Keywords: Escherichia coli, Diarrheal stools, Multidrug-resistance, Antibiotics, Kipe/Conakry