Abstract
Is there a Relationship between COVID-19 Infection and the Occurrence of Anencephaly? Observation of the Maternity of Mohammed the VI University Hospital of Marrakech
Bouchra Fakhir, Mohamed Hicham Abdelkhalki*, Yassir Ait Benkaddour, Karam Harrou, Ahlam Bassir, Abderrahim Aboulfalah, Hamid Asmouki, Abderraouf Soummani
Corresponding Author: Abdelkhalki Mohamed Hicham, Doctor Resident in Department of Obstetrics & Gynecology, Faculty of Medicine and Pharmacy, Cadi Ayyad University, Marrakech, Morocco.
Revised: July 27, 2023; Available Online: July 27, 2023
Citation: Fakhir B, Abdelkhalki AM, Benkaddour YA, Harrou K, Bassir A, et al. (2023) Is there a Relationship between COVID-19 Infection and the Occurrence of Anencephaly? Observation of the Maternity of Mohammed the VI University Hospital of Marrakech. J Infect Dis Res, 6(S3): 03.
Copyrights: ©2023 Fakhir B, Abdelkhalki AM, Benkaddour YA, Harrou K, Bassir A, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Introduction: Morocco has experienced, like the whole world, the COVID-19 pandemic. A subjective observation of the increase in the number of anencephalies lead us to conduct an observational study in order to see the relation between the pandemic and the occurrence of anencephaly. Since the teratogenic potential of the SARS Cov 2 virus and the physiopathology of anencephaly is not well documented, this work takes on its full importance.

Aim: the objective of the study is to look for eventual relation between the occurrence of anencephaly and the pandemic.

Material and methods: This is a retrospective study (from June 1, 2020 to May 31, 2022 in the Obstetrics Gynecology department, Faculty of Medicine and Pharmacy, CADI AYYAD UNIVERSITY Marrakech Morocco) consisting of the analysis of the number of patients in the target embryonic period (namely the closure of the neural tube: D18 to D30 of embryonic life) compared to the reference curves of the evolution of the SARS Cov2 pandemic.

Results: The analysis of the number of patients at the target embryonic phase shows that many of our anencephalons (63%) were conceived during periods of high diffusion of the SARS Cov 2 virus in Morocco.

Conclusion: Our study suggests a relationship between the COVID-19 pandemic and the occurrence of anencephaly, we cannot, however, highlight the type of direct or indirect relationship that binds them. Therefore, further studies should be considered to better investigate this relationship.

Keywords: Anencephaly, Closure Neural Tube Anomaly, COVID-19, SARS Cov2, Malformation, Pandemic