Is Mesenteric Ischemia in COVID-19 Patients a Surprise?
Talar Vartanoglu Aktokmakyan*, Merve Tokocin, Serhat Meric and Fatih Celebi
Corresponding Author: Talar Vartanoglu Aktokmakyan, General Surgery Department, Istanbul Bagcilar Training and Research Hospital, Merkez Street, Istanbul 34200, Turkey
Revised: December 12, 2020; Available Online: December 22, 2020
Citation: Aktokmakyan TV, Tokocin M, Meric S & Celebi F. (2020) Is Mesenteric Ischemia in COVID-19 Patients a Surprise? J Infect Dis Res, 3(S3): 28.
Copyrights: ©2020 Aktokmakyan TV, Tokocin M, Meric S & Celebi F. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Aim: The disease caused by the 2019 novel coronavirus is known predominantly for its respiratory outcomes; a subset of critically ill patients demonstrates clinically remarkable hypercoagulability in which thrombotic events range from acute pulmonary embolism in patients with COVID-19 pneumonia to extremity ischemia. Our observational study aimed to describe the incidence and characteristics, as well as clinical outcomes, of patients presenting and treated for mesenteric ischemia during the COVID-19 pandemic.

Material and Methods: Between March 13 and May 13, 2020, 60 patients operated for emergency reasons were analyzed, and it was noticed that 5 of the 6 COVID-positive patients were operated due to mesenteric ischemia.

Results: Five of sixty patients (83.3%) applied to our emergency clinic with COVID-19 positive and acute abdomen. Two of them (40%) did not have any comorbidities. All of them (%100) were male. There were no complications and only 1 death (20%). Mean leukocyte, neutrophil, and platelet levels were within the normal range, while the lymphocyte level was near the lower limit. C-Reactive Protein was above the limit in all patients. The mean levels of International Normalized Ratio, Platelet, and Activated Partial Thromboplastin Time were above the limits. While D-dimer levels were close to the upper limit; fibrinogen levels were above the normal limit for each patient.

Conclusion: The presence of hypercoagulation status in critical COVID-19 patients should be observed closely, and anticoagulation therapy can be considered in selected patients. More clinical data are needed to examine the role of anticoagulation in COVID-19 treatment.

Keywords: COVID-19, Hypercoagulability, Mesenteric ischemia