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Esophageal
varices incidences are increasing by nearly 5% every year. Esophageal varices
are the causes of bleeding in approximately 18% of hospital admissions for
upper GI bleeding.
Objective: The purpose of this
study is to understand the cause, clinical manifestations and treatment course
for esophageal varices.
Material and methods: Detailed clinical
history and physical examination was done. All the pertinent investigations
were studied thoroughly of the selected case.
Results: The esophageal
varices is confirmed with the help of upper gastrointestinal gastroscopy and
repaired by banding.
Conclusion: Esophageal varices
usually go undiagnosed due to early common symptoms. Hematemesis is one of the
suggestive of esophageal varices and OGD is only the confirmative diagnosis for
it. The prognosis depends usually better if treatment received on time.
INTRODUCTION
Esophageal varices are abnormal, enlarged veins
in the tube that connects the throat and stomach. Variceal rupture is governed
by Laplace's law. Increased wall tension is the end result of increased
intravariceal pressure, increased diameter of the varices and reduced wall
thickness. The variceal wall thickness can be evaluated visually by the
presence of red wale markings. These markings reflect areas where the wall is
especially thin [1]. Variceal rupture often occurs at the level of the
gastroesophageal junction, where the varices are very superficial and thus have
thinner walls. Esophageal varices are the major complication of portal
hypertension [2].
RISK
FACTORS
·
Large esophageal varices
·
Red marks on the esophageal varices as seen on a
lighted stomach scope (endoscopy)
·
Portal hypertension
·
Severe cirrhosis
·
A bacterial infection
·
Excessive alcohol use
·
Excessive vomiting
·
Constipation
·
Severe coughing bouts
DIAGNOSTIC
INVESTIGATIONS
·
Blood tests
·
Endoscopy
·
Imaging tests, such as CT and MRI scans
ESOPHAGEAL
VARICES SYMPTOMS
·
Hematemesis
·
Stomach pain
·
Light-headedness or loss of consciousness
·
Melena (black stools)
·
Bloody stools (in severe cases)
·
Shock (excessively low blood pressure due to blood
loss that can lead to multiple organ damage)
TREATMENT
Therapeutic approaches are variceal ligation
(banding) and sclerotherapy. Banding is a medical procedure which uses elastic
bands for constriction. Banding may be used to tie off blood vessels in order
to stop bleeding, as in the treatment of
Sclerotherapy is a form of
treatment where a doctor injects medicine into blood vessels or lymph vessels
that causes them to shrink. It is commonly used to treat varicose veins or
so-called spider veins. The procedure is non-surgical, requiring only an
injection.
CASE
STUDY
An 85 year old patient with known
case of diabetes mellitus, hypertension since last 20 years and status post
percutaneous transluminal coronary (2002, 2011 and 2015). Patient had no
history of any bad habits like cigarette smoking, alcohol consumption or any
other drug substance. Patient was found semiconscious at home at night suddenly
and when aroused by relatives, patient had hematemesis of around 500 ml at
home. Patient was brought to hospital. The patient had complaints of malena and
acidity since one week. Patient was investigated in the form of alkaline
phosphatase, alpha fetoprotein, serum glutamic pyruvic transaminase, SGOT, bilirubin,
glucose, IgG, CBC, USG KUB, ABG, Electrocardiogram, APTT, ESR, USG whole
abdomen.
CBC shows Hb less than 7 g/dl.
USG whole abdomen was suggestive of reduced size of liver with diffusely
altered echo texture and surface irregularity, suggestive of chronic liver
parenchymal disease. Few small tortuous mesenteric venous collaterals, could be
suggestive of portal hypertension.
Upper gastrointestinal
gastroscopy was suggestive of esophageal varices. One band applied
endoscopically and further, patient was managed with anti-diabetics, antacid,
analgesic, antibiotic, beta blocker, statin and other supportive care.
CONCLUSION
Esophageal varices usually go undiagnosed
until hematemesis occur. Hematemesis is a medical emergency and always occur
due to upper GI tract bleeding. The color is usually bright red in color. The
hematemesis is treated with somatostatin analogue (e.g. Octreotide) or
vasopressin (e.g. Terlipressin); it helps to reduce splanchnic blood flow. The
Glasgow-Blatch Ford Bleeding scoring system score is used to determine the
risk. This scale is purely based on clinical and biochemical parameters. The
warning signs of esophageal varices is dizziness even when awake, weight loss,
low Hb level, complaints of acidity, heartburn, hematemesis and malena.
Patients with hypertension and diabetes have
poor prognosis as medicines have adverse effects on liver which can lead to
liver cirrhosis and portal hypertension as well. At advanced age, the banding
is done for symptomatic treatment only as no other option is available at this
age.
1. Hilzenrat N, Sherker AH (2012) Esophageal varices: Pathophysiology,
approach and clinical dilemmas. Int J Hepatol 2012: 35-40.
2. Maruyama H, Yokosuka O (2012) Pathophysiology of portal hypertension and
esophageal varices. Int J Hepatol 2012: 38-42.
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