2571
Views & Citations1571
Likes & Shares
Neoadjuvant
chemotherapy (NAC) of rectal cancer has some advantages: 1) Whole body control
from the early stage of treatment; 2) Tumor reduction (favorable for
laparoscopic surgery); 3) No functional failure due to radiation.
In this
study, a total of 50 patients with rectal cancer, treated with NAC, were
examined. The pathological primary cancer area and the radiological cancer
volume reduction ratio were measured using CT and/or MRI imaging and the
donut-shaped measurement method. Immunostaining of cytokeratin AE1/AE3 was
performed to quantitatively measure the cancer cell mass in the largest section
of rectal cancer. Cytokeratin AE1/AE3-stained area (P=0.04), mitosis (P=0.0027)
and radiological donut-shaped images after NAC (P=0.010) were lower in the high
radiological cancer volume reduction ratio group compared with the low
radiological cancer volume reduction ratio group.
QUICK LINKS
- SUBMIT MANUSCRIPT
- RECOMMEND THE JOURNAL
-
SUBSCRIBE FOR ALERTS
RELATED JOURNALS
- Journal of Nursing and Occupational Health (ISSN: 2640-0845)
- Journal of Ageing and Restorative Medicine (ISSN:2637-7403)
- Chemotherapy Research Journal (ISSN:2642-0236)
- Journal of Cancer Science and Treatment (ISSN:2641-7472)
- Journal of Pathology and Toxicology Research
- Advance Research on Alzheimers and Parkinsons Disease
- Journal of Blood Transfusions and Diseases (ISSN:2641-4023)