Abstract
Psychiatric Changes in Amyotrophic Lateral Sclerosis Patients and their Relatives
Gleb Levitsky*
Corresponding Author: Gleb Levitsky, Gleb Levitsky clinic, Russia.
Accepted: April 24, 2021. Available Online: April 29, 2021
Citation: Levitsky G. (2021) Psychiatric Changes in Amyotrophic Lateral Sclerosis Patients and their Relatives. J Neurosurg Imaging Techniques, 6(S1): 04.
Copyrights: ©2021 Levitsky G. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Share :
  • 412

    Views & Citations
One hundred eighteen amyotrophic lateral (ALS) sclerosis patient and 97 their family members were examined by psychiatrists. Assessment was performed by Hamilton depression score (HAM-D) for a ll and frontotemporal dementia score for patients. Psychiatric changes were revealed in 101 (85%) of ALS patients and in 51 (52.5 %) of family members that were significantly lower than in ALS patients, p<0.05). The average score by HAM-Din ALS patients with situation-mediated depression comprised. 17±4, with situation mediated anxiety disorder it was 15±5, and with situation mediated anxiety and depression disorder it was 21±6 (p>0.05 between groups). The average degree by HAM-D in family members comprised 12±4, with situation-mediated anxiety disorder it was 22±5 (р<0.05 in comparison with the latter estimate), and with situation-mediated anxiety and depression disorder it was 16±6.The spectrum of situation mediated psychiatric impairments were equally represented with subtle predominance of situation-mediated depression. Rare cases of coincidence of ALS with major psychiatric disorders were described. In 33 of ALS patients (28%) frontotemporal cognitive changes were seen, that reached the level of dementia in 4.2% of cases. Among family members only situation-mediated psychiatric disorders were revealed with marked predominance of anxiety disorder (28%, p<0.05). Habitual intoxications were seen in 49ALS patients (41.5%) and 80 family members (82.4%) (p<0.05). High prevalence of anxiety disorder leads to denial in cooperation with professional doctors (73-76%), denial of aggressive treatments (74.5%), appeal to scammers and irrelevant expenses (29.6% случаев). Dual patronage of ALS families is recommended by psychiatrists and narcologists in individual cases, what may increase number of life-sustaining treatments in ALS and the increase of life quality in ALS patients and family members.

Keywords: Psychiatric disorders, Amyotrophic lateral sclerosis, Frontotemporal dysfunction, Habitual intoxications