Dr. Jian-Min Zhang is a professor and principle investigator of Zhejiang University School of Medicine, and the academic leader of neurosurgery, which is ranked as the National Key Discipline of the Ministry of Health. He graduated from Zhejiang Medical University and received his bachelor’s and doctor’s degree in the year 1983 and 2005 respectively. He is also the member of standing committee of Neurosurgery Branch of Chinese Medical Association; at the same time serves as the member of standing committee and vice chief of Neurosurgery Branch of Chinese Medical Doctor Association. Now Dr. Jian-Min Zhang is in charge of various projects granted by National Natural Science Foundation, National Major Research Program, etc. Recently, he was honored as the chief accomplisher with many awards including the third price of Provincial Science and Technology Progress Award, the first price of Lim Por Yen High Scientific and Technological Award. The long-term goal of his lab was to investigate translational medicine in neurosurgery, establish the effective evaluation of nervous system diseases, solve the major scientific problems and critical technologies in diagnosis and treatment, and apply brain-computer interface to the nervous system. Moreover, in the research of aneurysmal subarachnoid hemorrhage, Dr. Jian-Min Zhang’s team is devoted to investigating the mechanism and the interaction of oxidative stress, inflammation and apoptosis in the development of cerebral angiospasm after SAH, searching for the new therapeutic target, and exploring the therapeutic strategy of new-type selective anti-oxidants. Up to now, significant research achievements have been obtained in cerebrovascular disease and functional nervous system disease, especially in the pathogenesis and treatment of subarachnoid hemorrhage and epilepsy. Representative papers were published in many famous international magazines including 《J Neuroinflammation》, 《Crit Care》 and 《J Neurosci Res》.

Dr. Jian-Min Zhang’s lab mainly focuses on the fundamental and clinical research into cerebral vascular disease and brain tumor. In terms of clinical medicine, he is specialized to the treatment of complicated diseases in neurosurgery and is expert in the diagnosis and treatment, especially the micro-neurosurgery, of various cerebral vascular diseases including aneurysm, arteriovenous malformation and Moyamoya disease. While for basic medicine, he is devoted to the research of translational medicine in neurosurgery, mainly comprised of two aspects: 1. By establishing the effective evaluation of nervous system diseases, solving the major scientific problems and critical technologies in diagnosis and treatment, investigating the brain-computer interface with two-way closed loop, and constructing the method of accurate real-time early-warning and the techniques of arousing the cerebral cortical responsiveness via electrical stimuli, to invent the principle prototype of cerebral cortex electrical stimulator with independent intellectual property right and to apply it to the treatment of nervous system diseases and clinical research; 2. By investigating the interaction and mechanism of oxidative stress, inflammation and apoptosis in cerebral angiospasm after SAH, and exploring the application of neuroprotective function of new-type selective anti-oxidant in treatment of cerebral angiospasm, to provide new therapeutic strategy for clinical medicine.