Reasearch and teaching in medicinal chemistry. (Antibiotics, anti-mutagenic, anti-cancer agents, cell biology. Method development and validations of analytical methods, quality control and quality assurance departments. cGMP, cGLP environment. Preparation and execution of protocols and standard operation procedures for analytical methods. Participated in auditing reports for FDA submissions (NDA and ANDAs). Operation of analytical instruments such as GC, HPLC, LC-MS/MS (antibiotics, immunosuppressant and anticancer agents) and AA etc. Operation of UV, FT-IR, NMR, MS and CD. Structural determination of new organic molecules with biological activity, stability, dissolution studies and analysis of pharmaceutical active ingredients from different matrices. Method development for bulk production of biologically active compounds from natural resources and/or semi-synthesis.
|Research Interest :
Chemotherapy, cell biology, drug discovery, molecular docking studies, medicinal chemistry pharmaceutical sciences