Editorial Board

Founder & Editor in Chief
Prof. Jyh-Cherng Ju, PhD

Prof. Jyh-Cherng Ju, PhD
Professor
Graduate Institute of Biomedical Sciences
China Medical University
Taiwan

  Biography :

Professor Ju earned his PhD training from Department of Animal Science, Cornell University, New York, USA, in 1998, and then came back Taiwan to work for National Chung-Hsing University, Taichung, Taiwan. In 2012, he moved to Graduate Institute of Biomedical Sciences, China Medical University (CMU) and the Hospital (CMUH), Taichung, Taiwan. He has been working on embryo/animal cloning by somatic cell nuclear transfer, pluripotent stem cells, particularly in domestic species, and thermal impacts on embryo development and germlayer differentiation. He has also established a Core Lab for Stem Cell Research in CMUH to differentiate human, as well as animal, ES cells into three germlayer cell lineages, such as motor neurons, cardiomyocytes and hepatocytes from normal and disease individuals, for research and therapeutic purposes.

Biography
  Research Interest :

Gamete Biology, Embryology, Animal cloning and embryonic stem cells, Reproductive Biology, Signal Transduction, Thermal Biology

Research Interest
Co- Editor in Chief
Prof. Yong Li

Prof. Yong Li
Associate Professor
Dept. of Pediatric and Orthopeadic Surgery
University of Texas
USA

  Biography :

Dr. Yong Li completed his medical education MD and Ph.D. training in China. He went to the Imperial College in London for his 1st postdoc fellowship, and then he started his 2nd postdoc associated job in the Children's Hospital of Pittsburgh. He was appointed a research assistant professor in 2002 and promoted to director of the molecular pathology laboratory and a tenure-track Assistant Professor of Orthopedics, Pathology, and Bioengineering of the University of Pittsburgh in 2005. Then he was appointed a laboratory director and Associate Professor of Center Stem Cell for Regenerative Medicine and Pediatric, Orthopedic and Internal Medicine of University of Texas Medical School in 2011. Dr. Li has more than one hundred peer-reviewed publications, and his team is well-funded through DOD and NIH grants. He has more than twenty national and international awards, including the Michael Miller Young Investigator Award from UPMC. He also was a student mentor for National Goldwater scholarship.

Biography
  Research Interest :

Dr. Li has extensive experience researching the molecular, cellular, and pathological processes within skeletal muscle. Specifically, much of his research has focused on TGF-beta related tissue injury and fibrosis in addition to the genetic and epigenetic regulations that occur during tissue repairing. Dr. Li is an expert on adult muscle stem cells, their plasticities, differentiation and regeneration capacity in cases of injury or disease. In the past several years, his team has developed several novel techniques for molecular, cellular, and small animal-based research that focuses on several major areas of basic scientific study: the mechanism cell migration and adhesions, the homeostasis of adult stem cells during injury or physical exercise, and the formation and prevention of fibrosis in injured and diseased tissues. He and his team also have leaded collaboration on translational studies that involve the use of products isolated from stem cells as well as the engineered platelet-rich plasma (PRP). Using these new genetic and epigenetic tools, Dr. Li and his team have successfully approached several key milestones in the field of stem cell study as it relates to aging, cancer, tissue injury, and tissue regeneration and engineering.

Research Interest
Editorial Board Member
Prof. Amal M. Mohamed

Prof. Amal M. Mohamed
Professor of Human Genetics, Director of the array CGH laboratory
Human Genetics and Genome research Division
National Research Centre
Egypt

  Biography :

Dr. Amal Mahmoud Mohamed, Professor of Human genetics, Human Cytogenetics department Human genetics & Genome Research Division, National Research Centre (NRC). Graduated at the Faculty of Medicine, Cairo University with distinction 1977. MSc. In clinical pathology, PhD in Human Genetics. Major research interests are: human cytogenetics research with its recent diagnostic techniques especially for intellectual disability and multiple congenital anomalies patients and data registry of genetic disorders. Participated in establishment of Human Genetics and Genome Research Division. Head of the division from 2003 to 2009, head of Cytogenetics Department 2009 to 2012. Currently the Head of Cytogenetic Team in STDF project for Centre of Scientific Excellence of Human Genetics in NRC. Director of the microarray laboratory. Deputy Editor of the Middle East Journal of Medical Genetics (MEJMG). General Secretary of the National Society of Human Genetics, Egypt. Head of the conference board of the 10th Conference of African Society of Human Genetics,16-18 N0vember 2017, Cairo, Egypt.

Biography
  Research Interest :

Fields of Interest: • Genetic diagnosis of Intellectual disability and or / Multiple congenital anomalies • Autism • Disorders of sex development • Genetic disorders of premature aging • Genetic testing using different techniques such as FISH, MLPA and array CGH.

Research Interest
Prof. Jin Seop Bak

Prof. Jin Seop Bak
Professor & Director
Dept. of Food Science & Biotechnology
Kyonggi University
Korea

  Biography :

Jin Seop Bak has a college-degree in Yonsei Univ., a MS/PhD in Korea Univ. with top-honors, and LittD/ScD/PhD in IBC (in Cambridge). He is/was in Faculty of Kyonggi Univ. and KAIST (as Project-Leader). He was appointed to the post of Secretary-General/Professor/Director General (for Asia)/Adviser in IBC. He worked as a researcher/scholar/judge especially in UC Berkeley (conditionally), Seoul National Univ. and MIT (conditionally). In Korea Univ., Prof. Bak played a key role in teaching Physical Chemistry. He is a leading member of many academies and nonprofit/profit organizations (e.g., Mensa). His main area of investigation is Life/Natural/Applied Sciences. He has achieved many publications, 2 patents, 14 grants. He is a reviewer of more than 55 journals, and member of 29 editorial boards. He has been cited especially in Marquis Who's Who and IBC.

Biography
  Research Interest :

I believe that my experiences make me both the ideal researcher and global leader for performing advanced highthrough put technological studies. Until now, I generally explored almost every possible academic endeavor, including Biological Sciences, Food Sciences, Natural Sciences, and Applied Sciences

Research Interest
Dr. Chun Hei Antonio Cheung Ph.D.(Auckland)

Dr. Chun Hei Antonio Cheung Ph.D.(Auckland)
Associate Professor
Department of Pharmacology and Institute of Basic Medical Sciences, College of Medicine
National Cheng Kung University
Taiwan

  Biography :

2016- Associate Professor Present Department of Pharmacology and Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Taiwan 2011-2016 Assistant Professor Department of Pharmacology and Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Taiwan 2007-2011 Post-Doctoral Research Fellow National Institute of Cancer Research, National Health Research Institutes (NHRI), Taiwan

Biography
  Research Interest :

Research Interest
Prof. Ishtiaq Qadri

Prof. Ishtiaq Qadri
Professor and Head Medical Biotechnology & Translational Research
King Fahd Medical Research Center
King Abdul Aziz University
Saudi Arabia

  Biography :

I was invited by the Higher Education Commission of Pakistan to establish a research center for the control and ultimate eradication of key viral diseases in Pakistan. Overall responsibility included capacity building, securing funds form national and international sources (over 5 million US $), development of curricula for PG and UG programs, management of PG programs/students and staff (300), establishment of 18 labs including a diagnostic facility.

Biography
  Research Interest :

Biotechnology, Biochemistry, Stomatology/Microbiology, etc

Research Interest
Dr. Jayant Kumar, MD, MS, MASTER IN HBP SURGERY, MRCS(EDINBURGH, U.K)

Dr. Jayant Kumar, MD, MS, MASTER IN HBP SURGERY, MRCS(EDINBURGH, U.K)
Academic Visitor
Faculty of Medicine, Department of Surgery & Cancer
Imperial College London
UK

  Biography :

Dr Jayant’s work at Imperial College London is assessing the role of Radiofrequency (RF) technique in the management of Liver and Pancreatic Cancer. He is particularly interested in the development of newer techniques of pancreatic and liver cancer management. His recent study on liver cancer "Assessing the impact and benefits of RF-assisted parenchymal sparing liver resection on post-hepatectomy liver failure" reflects the development of the RF-assisted liver resection using the Habib-4X as a feasible and safe technique of liver resection with a low incidence of post-hepatectomy liver failure and related mortality. He also works on the project "RF-assisted pancreaticodudenectomy for locally advanced pancreatic adenocarcinoma- A novel approach" which leads to the development of newer RF-assisted pancreaticoduodenectomy technique which is more feasible and safer than a vascular resection with a conventional technique. Dr Jayant holds an MD certification, a Master in Hepatobiliary and Pancreatic Surgery from Imperial College London & HBHI and successfully cleared his MRCS from Royal College of Surgeons Edinburgh along with that he is also on college role of the University of Liverpool for the Master in Transplant Surgery.

Biography
  Research Interest :

Research Interest
Dr. Mohamed Elgendy

Dr. Mohamed Elgendy
Research Project Leader
INDICAR programme
University of Vienna
Austria

  Biography :

Experienced researcher in biomedical sciences with focus on cancer biology. Combine solid track record of basic and translational research in several established European labs with 5 years of clinical practice. Motivated by challeneges, eager to dicover more and genuinely fascinated by science.

Biography
  Research Interest :

Cancer Metabolism, Cell Death, Autophagy, Signaling in Cancer.

Research Interest
Prof. Jim Jinn-Chyuan Sheu (AKA. Chin Chuan Hsu;許晉銓), PhD

Prof. Jim Jinn-Chyuan Sheu (AKA. Chin Chuan Hsu;許晉銓), PhD
Professor
Human Genetic Center, China Medical University Hospital, Institute of BioMedical Sciences
National Sun Yat-sen University
Taiwan

  Biography :

Prof. Sheu’s research interest focuses on identification and characterization of tumor-associated genes by using genomewide technologies and functional studies. In the past years, he had defined Rsf-1, also known as HBXAP, as a potent cancer-driving gene during cancer development and progression [1]. Significantly, Dr. Sheu demonstrated the interaction between Rsf-1 and SNF2H as the key for promoting oncogenic signaling in cancer cells, resulting in gross tumor growth [2] and drug resistance [3]. These findings enable Rsf-1 as an attractive target for new therapy development [4]. In recent years, Dr. Sheu’s studies further pointed out that Rsf-1 overexpression serves as a selecting barrier to allow outgrowth of cell clones with genetic defects in self-surveillance [5], that subsequently ease cancer cells to accumulate more genetic alterations [6]. Similar mechanism was found applicable for BRAF oncogenic mutations at caner initiation stage [7]. Achievements of those studies made Dr. Sheu won “Marquis Who’s Who in the World” in 2013, and the National Science Council (now the Ministry of Science and Technology) “Academic Research Award-Wu-Da-You Memorial Award” in 2014. In addition to functional characterization of Rsf-1, Dr. Sheu initiated his studies on head and neck cancer including oral squamous cell carcinoma (OSCC) and nasopharyngeal carcinoma (NPC). Based on comparative analyses between genomic and transcriptome maps, Dr. Sheu has successfully validated EGFR activation, either through gene amplification/overexpression or activation of down-stream targets, is the most frequent genetic event in OSCC [8]. On the other hand, deletion of 3p12.3-p14.2 and amplification of 3q26.2-q26.32 serve as genomic markers for advanced NPC [9], which might be the footprints of frequent Epstein-Barr virus reactivation [10]. Based on above findings, Dr. Sheu found LRIG1, a negative regulator for EGFR signaling, as a tumor suppressor in head and neck cancer through down-regulation of EGFR ligands and extracellular remodeling activity [11]. Using similar approach, Dr. Sheu also identified TLN1 amplification/over- expression responsible for OSCC migration and invasion, thus could be utilized as a good therapeutic target [12]. Furthermore, Rsf-1 [13] and haptoglobin [14] were found as valuable biomarkers for predicting clinical outcome and tumor recurrence of OSCC. Other interesting findings regarding cancer-driving genes in head and neck cancer are under preparation for paper submission. For examples, we recently discovered a novel keratin fusion event in OSCC by NGS technology. Several fusion isoforms were defined and some of them were found correlated with worse clinical outcome [ROC and US patents][15, 16]. We are currently studying biofunctions of these fusion types to see if keratin fusion could be a newly defined mechanism for squamous cell transformation and cancer development. With the working experiences on tumor-associated genes, Dr. Sheu therefore holds the knowledge and key techniques/materials to define the oncogenic signaling networks of newly defined oncogenes.

Biography
  Research Interest :

Cancer Genetics and Genomics, Epigenetics, Chromatin Remodeling, Signal Transduction Profiling, New Drug Discovery & Development, Complementary & Alternative Medicine, Antibody/Vaccine Engineering

Research Interest
Prof. Xuesong YANG, MD, PhD

Prof. Xuesong YANG, MD, PhD
Professor and Dean
Department of Clinical Medicine
Jinan University Medical College
China

  Biography :

Xuesong Yang is currently a professor in, Jinan University Medical College, China. He received his bachelor’s and master’s degree in Harbin Medical University, China and then received his doctorate in Tokyo Medical and Dental University School of Medicine, Japan. After having worked in University of Manchester and University of Dundee University, UK respectively, he took the position in Jinan University Medical College. His research interests contain: 1) exploring embryos as the possible models for stem cell applications on regenerative medicine. 2) the regulations of coordinated signaling pathways on mesoderm and neural crest cell migration during gastrula embryo development. 3) the investigation of gene-regulatory elements on birth defects. 4) medical education researches. So far, he has published 101 SCI scientific papers including Developmental Cell, PNAS, Current Biology and Development, Developmental Biology and Oncogene.

Biography
  Research Interest :

Xuesong Yang is currently a professor in Division of Histology and Embryology, Medical College, Jinan University, China. He received his bachelor’s (MD) in clinical medicine from Harbin Medical University (1984), master’s degree in reproductive physiology from Harbin Medical University Division of Physiology (1987), and then started his overseas study in Japan (1991) after serving as an assistant professor in Harbin Medical University Medical College for two years. He received his doctorate in cell membrane physiology and neurosciences in Tokyo Medical and Dental University School of Medicine, Japan (1997). Next, I had worked on pancreas exocrinology as a postdoctoral research associate in University of Manchester for two years, and then moved to University of Dundee Wellcome Trust Center in 1999. Since then my research has mainly focused on developmental biology, specifically about “FGF, VEGF and PDGF signaling modulating mesoderm cell migration during chick embryo gastrulation”. Part of the work has been published in Developmental Cell, PNAS, Current Biology and Development, Developmental Biology and Oncogene. Since being recruited as a professor in Jinan University Medical School (2008), China, He has been continuing to carry on the aforementioned projects while he also extends his research interest into studying neural crest formation, neural tube formation & heart formation, and vasculogenesis & angiogenesis during embryonic development and corresponding congenital malformations as well as underlying mechanisms in the setting of various external teratogens using mouse and chick embryo models and human samples. Some of research results have already been published as shown in the following publication list.

Research Interest
Prof. Ssang-Goo Cho, Ph.D.

Prof. Ssang-Goo Cho, Ph.D.
President & Director of IDASI
Department of Stem Cell & Regenerative Biotechnology
Konkuk University
Korea

  Biography :

Ssang-Goo Cho received B.S., M.S., and Ph.D. degrees in Genetic Engineering from Korea University, Republic of Korea. He was awarded a postdoctoral fellowship at Ruttenberg Cancer Center, Mount Sinai School of Medicine, New York, USA and worked at Korea University as a research professor and at Institut Pasteur as a visiting scientist. Now, he has been serving as a professor at the department of Stem Cell & Regenerative Biotechnology, Konkuk University and also as a director of Incurable disease animal model and stem cell institute (IDASI). His areas of expertise include signaling pathways in stem, cancer, and cancer stem cells, molecular mechanism of cellular reprogramming, and apoptosis or autophagy, pancreatic beta-cell differentiation. He has published more than 130 papers in scientific journals.

Biography
  Research Interest :

Signaling pathways in stem, cancer, and cancer stem cells, Molecular mechanism of cellular reprogramming, Apoptosis and autophagy, Cancer stem cells, induced pluripotent stem cells, Pancreatic beta-cell differentiation, Pancreatic cancer cells.

Research Interest
Prof. Wei-Chien Huang Ph.D.

Prof. Wei-Chien Huang Ph.D.
Professor and Associate Dean
Department of Research & Development
China Medical University
Taiwan

  Biography :

Major awards and honors 1. Teacher Award for Outstanding Teaching Performance, College of Medicine, China Medical University 2012 2. Young Scholar Award for Medical Research, Professor C. Y. Lee Foundation,2007.11.10 3. Young Research Scholar Award, The Pharmacological Society in Taiwan, 2006.03.18 4. Excellent Ph.D. thesis Award of Wang Ming-Ning Memorial Foundation, Wang Ming-Ning Memorial Foundation, 2004.12.15 5. Graduate Travel Award,American Society for Biochemistry and Molecular Biology, 2004.03.12

Biography
  Research Interest :

Pharmacology, Signal transduction, Cancer Biology, Epigenetics, Molecular Biology, Drug resistance

Research Interest