|El Anzi Ouiam*, Sqalli Asmae, Maouni Safae, Meziane Mariam, Hassam Badredine|
|Corresponding Author: El Anzi Ouiam, Department of Dermatology-Venereology, Ibn Sina University Hospital, Mohammed V University, Rabat, Morocco|
|Received: December 05, 2018; Accepted: December 10, 2018; Published: February 12, 2019;|
|Citation: Ouiam EA, Asmae S, Safae M, Mariam M, Badredine H. (2019) Dermoscopic Features in Two Cases of Verrucous Epidermal Neavus. J Clin Trials Res, 2(1): 48-49.|
|Copyrights: ©2019 Ouiam EA, Asmae S, Safae M, Mariam M, Badredine H. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.|
Epidermal nevi are hamartomatous proliferations of the epithelium.
We report two cases of verrucous epidermal neavus (VEN) with new dermoscopic feature for diagnosis. On dermoscopic evaluation, we observed in both cases cerebriform pattern and large brown circles which are specific for the diagnosis of VEN.
Keywords: Verrucous epidermal neavus, Dermoscopy, Cerebriform, Brown circles
Epidermal nevi are hamartomatous proliferations of the epithelium which, in their different variants, can involve all the structures of the epidermis . We report two cases of verrucous epidermal nevus (VEN) with dermoscopic feature for diagnosis.
30 year old man presented with multiples papules on his forehead that he had had since he was thirteen. On clinical examination, we observed multiples hyper pigmented, keratosis and polycyclic plaques (Figure 1).
11 year old boy consulted for similar lesions on the left cheek. The lesions had been present since five years. Physical examination finds some brownish papule coalesce to form a serpiginous plaque (Figure 2).
On dermoscopic evaluation, we observed in both cases a cerebriform pattern with pseudo-comedones and nib borde (Figure 3), as well as large brown circles with variable dimensions and are located at the periphery or in the middle of the lesion (Figure 4). The histopathology showed features of verrucous epidermal naevus.
No difference between adult and pediatric appearance was noticed.
Various dermoscopic studies of sebaceous hamartomas or seborrheic keratosis have been published. However, few dermoscopic descriptions of VEN had already been made .
According to Canning, epidermal nevi present dermoscopically a cerebriform pattern, more often associated with seborrheic keratosis. Carbotti  has described, as we do, brown circles that may correlate histologically with the characteristic arrangement of pigmented keratinocytes surrounding the dermal papillae and which may be considered a characteristic feature of VENs.
Cerebriform pattern and large brown circles represent a specific dermoscopic feature for the diagnosis of verrucous epidermal nevus.
1. Lozano B (2017) Dermoscopic features in three cases of rounded and velvety epidermal naevus. Australas J Dermatol 58: 325-326.
2. Carbotti M (2016) Dermoscopy of verrucous epidermal nevus: Large brown circles as a novel feature for diagnosis. Int J Dermatol 55: 653-656.
- Stem Cell Research and Therapeutics(ISSN:2474-4646)
- Oncology Clinics and Research(ISSN: 2643-055X)
- Journal of Renal Transplantation Science(ISSN:2640-0847)
- International Journal of Surgery and Invasive Procedures(ISSN:2640-0820)
- Immunology Clinics and Research
- Journal of Immunology Research and Therapy(ISSN:2472-727X)